Let's Understand the Chemistry
Ensuring the chemistry and composition of a substance or product is fully characterised and accurately reported is a fundamental requirement for regulatory compliance under REACH, Biocidal Products Regulations, and Plant Protection Products Regulations. At Blue Frog Scientific, we provide expert regulatory and technical chemistry support, helping clients generate, interpret, and submit high-quality physico-chemical and product characterisation data.
Comprehensive Chemistry & Regulatory Compliance Services
Our team consists of experienced analytical and regulatory chemists, ensuring that our client's obligations under EU and UK regulatory frameworks are understood and applied correctly when assessing and reporting chemical properties and product behaviour.
Our services include:
- Substance Identification & Characterisation – Supporting the generation, interpretation, and submission of analytical data for precise substance identity confirmation
- Physico-Chemical Testing & Hazard Assessment – Conducting and overseeing studies on key physico-chemical endpoints, ensuring regulatory compliance
- Product Characterisation & Behavioural Properties – Evaluating formulations, stability, and performance of biocidal and plant protection products
- Analytical Support for Toxicological & Ecotoxicological Studies – Providing high-quality analytical chemistry expertise to ensure accurate dosing, test system exposure, and degradation/metabolite analysis
Physico-Chemical Property Assessments
We support comprehensive physico-chemical testing for chemical substances, biocides, and plant protection products, ensuring compliance with OECD, CIPAC, and EU test guidelines.
- Substance Identity & Composition – Molecular structure, purity, and impurity profiling
- Physical State & Appearance – Including colour, odour, and state at standard conditions
- Melting/Freezing Point (OECD 102) – Determining phase transition temperature
- Boiling Point (OECD 103) – Establishing volatility and thermal stability
- Density & Relative Density (OECD 109) – Measuring bulk and tap density for solids/liquids
- Vapour Pressure (OECD 104) – Assessing volatility for exposure modelling
- Surface Tension (OECD 115) – Relevant for environmental fate assessments
- Water Solubility (OECD 105) – Key for risk assessment and bioavailability predictions
- Partition Coefficient (OECD 107, 123) – Log Kow determination for bioaccumulation potential
- Dissociation Constants (OECD 112) – Ionisation behaviour across pH ranges
- Stability Testing – Hydrolytic stability, thermal stability, and storage conditions
Product Characterisation for Biocides & Plant Protection Products
In addition to substance-level assessments, biocidal products and plant protection products require detailed formulation characterisation to assess physical behaviour, stability, and application properties.
- Storage Stability & Shelf-Life (CIPAC MT 46, OECD 113) – Evaluating long-term chemical integrity
- pH & Acidity/Alkalinity (OECD 122, CIPAC MT 75.3) – Measuring chemical stability in aqueous formulations
- Oxidising Properties (UN Test O.1, CIPAC MT 39) – Assessing potential for hazardous reactions
- Surface Tension & Foaming Properties (CIPAC MT 47, OECD 115) – Relevant for spray formulations
- Suspensibility & Wettability (CIPAC MT 15, MT 53.3) – Ensuring homogeneous product dispersion
- Particle Size Distribution (OECD 110, CIPAC MT 187) – Impacting formulation stability & application efficiency
- Viscosity & Flow Properties (OECD 114, CIPAC MT 22, MT 192) – Ensuring sprayability and application consistency
- Corrosion Properties (OECD 111, CIPAC MT 34) – Evaluating packaging compatibility & storage risks
Study Monitoring & Regulatory Services
Our team of experts will ensure that chemistry data are generated to the required reliability and relevance for submission, and ensure their seamless integration into registration dossiers and chemical safety assessment.
- Physico-Chemical Data Gap Analysis – Identifying missing information and optimising testing strategies for cost-effective compliance
- Study Design & Monitoring – Supporting Good Laboratory Practice (GLP) studies with Contract Research Organisations (CROs)
- Regulatory Dossier Preparation & Submission – Ensuring physico-chemical data is correctly formatted for submission
- Regulatory Advocacy & Compliance Support – Assisting with competent authority queries, study waivers, and scientific justifications
At Blue Frog Scientific, we deliver high-quality, regulatory-compliant chemistry assessments, ensuring that your chemical, biocidal, and plant protection product dossiers are scientifically robust and meet EU and UK regulatory expectations.
Contact us today to discuss your physico-chemical and product characterisation requirements.
